Turbulence is an ubiquitous phenomenon in natural and industrial fluid flows. Yet, it still lacks a satisfactory theoretical description. One of the main open issues is to calculate the statistical properties of the turbulent steady state, and in particular what is generically called intermittency effects, starting from the fundamental description of the fluid dynamics provided by Navier-Stokes equation. In this presentation, I will focus on isotropic and homogeneous turbulence in three-dimensional incompressible flows.